SARMS UK
Haeba u phahamisa khafetsa, mohlomong u batla ho betla setopo sa ho qetela. Boikarabello bo bong le bo bong ke lejoe le hatang ho fihlela phihlello ea methapo eo u e batlang. Le ha o sebetsa ka thata, ho bonahala o ke ke oa fihlela sepheo sa hau. U phahamisa letsatsi le leng le le leng. U ja liprotheine tse ngata. Empa ha o hahe mesifa e lekaneng ho shebahala e sehile ebile e otile. Ebile, u hole le eona.
Batho ba bangata ba sebetsa ka thata empa ha ho mohla ba fihlelang ponahalo eo e hahohileng. Leha ho le joalo, ho na le tsela ea ho fumana mofuta oa 'mele oo u o lakatsang haholo. Kgaoletso ha o batla. Mohlomong u utloile ka eona - li-SARM.
Selective androgen receptor modulators, kapa li-SARM, ke sehlopha se secha sa tlatsetso se bitsoang "steroids ea molao." Li-SAR ke lithethefatsi tse matlafatsang ts'ebetso ea hau ea liatleletiki le mesifa e boima. Ba fihlela sepheo sena ka ho etsisa litlamorao tsa testosterone. Ho feta moo ke hore li-SAR ha li na litla-morao tseo li-steroid li nang le tsona, joalo ka ho fokotsa testicles ea hau le ho baka pherekano ea maikutlo.
Leha ho na le polokeho e lekanyelitsoeng ho li-steroids, ho na le ngangisano e kholo ka li-SAR hona joale. Mohlomong u utloile hore ba ka ba le litla-morao tse kotsi. Mohlomong u ntse u ipotsa hore na u nka li-SARMS joang kapa ha li na kotsi. Sehloohong sena, re tla sheba ka botebo li-SARM tse fapaneng hore o tsebe ho nka qeto ea hore na litlatsetso tsena li u loketse.
Mabapi le li-SARM
Li-androgen receptor modulators (SARMs) ke pokello ea metsoako e sebetsanang le lihormone tsa hau ka tsela e shebiloeng haholo. Li-SAR li qapiloe ke bo-ramahlale lilemong tse mashome tse fetileng ho sebetsana le liphetoho tse amanang le lilemo matleng le mesifa e qalang lilemong tse bohareng. Boithuto bo ileng ba lekola li-SARM qalong bo ne bo shebile bohlokoa ba bona ho batho ba hlaphoheloang opereisheneng la letheka, basali ba kamora ho ilela khoeli le bakuli ba mofets'e. Morero e ne e le ho thusa ho fokotsa menyetla ea ho oela mesifa e fokolang ho batho ba baholo, ho fokotsa ho se ts'oanelehe ho tsamaeang ka moroto ho amanang le mesifa e fokolang ea noka le ho ntlafatsa matla a bakuli ba mofets'e.
Seo bafuputsi ba se fumaneng litekong tsena tsa bongaka ke hore li-SARM li chesa mafura le ho aha mesifa boemong bo ts'oanang le li-steroids. Ho feta moo, li-SAR li entse lintho tsena ntle le litlamorao tse mpe tse bonoang ka li-steroids. Bafuputsi ba fihletse qeto ea hore lipatlisiso tse ling li hlokahala ho li-SARM ho tseba polokeho ea ts'ebeliso ea bona ea nako e telele. Leha ho le joalo, batho ba fumane ka melemo ea li-SARM mme ba qala ho e tlatselletsa. Liketekete tsa banna ba tsoang maemong ohle a bophelo ba sebelisa li-SARM ho aha mesifa le ho fokotsa mafura.
Melemo ea li-SARM
Mona ke melemo ea li-SARM.
- Haha mesifa e mosesane. Li-SAR li loketse mang kapa mang ea batlang ho aha mesifa ka potlako.
- Tshela mafura. Li-SAR li fumanoe li thusa ho fokotsa boima ba mafura. Metsoako ena e ka thusa ho tšolla mafura.
- Eketsa masapo a masapo. Phuputso e 'ngoe e phatlalalitsoeng ke bafuputsi Univesithing ea Ohio State e fumane hore li-SARM li ekelitse matla a masapo haholo ha li ntse li fokotsa mafura. Bafuputsi ba ile ba etsa tlhahiso ea kalafo ea SARM e le mokhoa oa ho fokotsa tahlehelo ea mesifa ho batho ba nang le lefu.
Mefuta ea li-SARM
Ho na le mefuta e fapaneng ea li-SARM tse fumanehang 'marakeng. SARM ea hau bakeng sa hau e ipapisitse le lipheo tsa hau. Li-SAR tse ling li molemo bakeng sa karolo ea ho itšeha 'me tse ling bakeng sa tlhokomelo. Mona ke mefuta e meholo ea li-SARM.
Ligandrol (LGD-4033)
Ligandrol kapa LGD-4033 e thehiloe ke Ligand Pharmaceuticals ho phekola ho senyeha ha mesifa ho bakuli ba nang le mofetše le mafu a mang. Hajoale e litekong tsa bongaka ho fumana tumello ea FDA. Motsoako ona o tsejoa e le e 'ngoe ea li-SAR tse matla ka ho fetisisa' marakeng. E lebisa ho katleho e kholo mesifa le matla. Litholoana tsa LGD-4033 ke tsa nako e telele, haholo ha li kopantsoe le li-macro tse nepahetseng.
Ostraine (MK-2866)
Ostraine kapa MK-2866 ke e 'ngoe ea li-SARM tse ncha tse fumanehang. Motsoako ona o ne o boetse o etselitsoe ho sebetsana le ho senyeha ha mesifa. E boetse e sebelisetsoa kalafo e nchafatsang ea testosterone. MK-2866 e hlahisa leruo la nako e telele le la bohlokoa ka matla le katleho ea mesifa. SARM ena le eona e fumanoe e eketsa bongata ba masapo. Ligandrol (LGD-4033) le Ostraine (MK-2866) ke li-SARMS tse tšoanang. Ithute haholoanyane ka tse peli tse posong ena ea blog ho bapisa LGD-4033 le MK-2866.
Cardarine (GW-501516)
Cardarine (GW-501516) ke SARM e seng ea lihormone. Motsoako ona, o bitsoang Endurabol, o qapiloe qalong ho li-1990 ke Ligand le GlaxoSmithKline ho fokotsa lihlahala. E lahliloe ke lik'hamphani tsena tsa meriana kaha e ne e sa sebetse molemong oo. Empa, ho ile ha sibolloa nakong ea liteko tsa bongaka hore setsi sena se makatsa ka tsela e ngoe. E tlosa mafura mme e ntlafatsa mamello haholo. Kajeno ke e 'ngoe ea mekhoa e tsebahalang haholo bakeng sa tahlehelo ea mafura le mamello.
Andarine (S4)
Joalo ka li-SAR tse ling, Andarine qalong e ne e reretsoe ho sebetsana le ho senyeha ha mesifa. Bo-rasaense ba fumane hore ke e 'ngoe ea li-SARM tse matla ka ho fetisisa tse sehang mafura ka ntle moo. S4 e loketse ho khaola mafura a manganga a mpa. Ka lebaka lena, e ratoa haholo ke ho seha lipotoloho. Andarine e boetse e ntle bakeng sa ho hohola, hape.
Li-stenabolic (SR-9009)
Motsoako ona ile ntshetswa pele bakeng sa baatlelete. E thusa ho eketsa mamello ebile e ntle bakeng sa tahlehelo ea mafura. SR-9009 e eketsa khalori e chesang ka liperesente tse 5. Stenabolic e pheta melemo ea boikoetliso leha mmele o phomotse. E khothaletsa matla, ts'ebetso le mamello.
Litla-morao tsa SARM
Joalo ka litlatsetso tsohle le meriana, li-SAR li na le litla-morao. Ho ea ka WebMD, hoo e ka bang meriana eohle - ho tloha ho aspirin ea mantlha ho isa ho SARM - e na le monyetla oa ho baka litlamorao. Boholo ba nako, litla-morao li etsahala feela ho basebelisi ba fokolang. Boholo ba litla-morao li nyane. Kotsi ea litla-morao tsa SARM ea eketseha haeba o nka ho feta tekanyetso e khothalletsoang ea letsatsi le letsatsi. Na u ntse u ipotsa hore na u ka nka SARMS joang ho qoba litlamorao? Mokhoa o bolokehileng ka ho fetisisa ke ho khomarela lethal dose.
Ha re phethela, li-SARMS li netefalitsoe ka mahlale hore li aha mesifa le ho chesa mafura. Li fana ka melemo e mengata e tšoanang ea ho aha 'mele ea li-steroid empa li se na litla-morao tse tebileng. Ingolise bakeng sa litšebeletso tse khethehileng le lipapatso. Ho latela litaba tsa morao-rao ka SARS, re latele.
References:
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2602589/
- https://www.nytimes.com/2018/04/12/well/move/sarms-muscle-body-building-weight-lifting-pill-supplements-safety.html
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2039878/
- https://www.webmd.com/a-to-z-guides/drug-side-effects-explained#1